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The peptide hormone hepcidin [65, 66], secreted primarily by hepatocytes, is the principal regulator of multiple events that lead to iron homeostasis [67], including dietary iron absorption, iron recycling by macrophages, and the release of iron from hepatic stores (Fig

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Growth Factor Modulation – The peptide has been shown to upregulate the expression of growth hormone receptors (GHR) in tendon fibroblasts